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Siegesbeckia
Orientalis Extract
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| Siegesbeckia
Orientalis Extract is obtained from the herb Siegesbeckia orientalis
L. This herb has been used for centuries externally to soothe
inflammation and stimulate wound healing, which it does through
tissue regeneration by way of collagen matrix build-up. |
| A
now expired patent by Pierre Fabre Medicaments describes its
ability to stimulate wound healing, to promote more regular
tissue renewal, to increase the normal appearance of scars and
to fully restore elasticity to damaged skin with collagen fibers
arranged in regular fashion. |
| Extracts
of Siegesbeckia orientalis have shown anti-inflammatory properties,
inhibition of collagenase and protection from UV induced erythema. |
| This
initial research led to an investigation of Siegesbeckia Orientalis
Extract ability to restructure stretch marks. Stretch marks
are caused by abnormal stretching of the dermis (pregnancy,
change in weight), from a linear scar or from some endocrine
disorders. In each case the stretch mark affects the elastin
fibers in the middle dermis, which are diminished or disappear.
Any effective treatment for stretch marks thus must restore
normal quantities of collagen and elastin fibers. |
| The
effects shown in a four-week clinical study where a crème
containing 1.5% of Siegesbeckia Orientalis Extract was applied
by volunteers twice daily are listed below. |
Results
| Length
of Streaks |
Reduced
52.15% |
| Surface
Smoothness |
Increased
13.7% |
| Indented
Surfaces |
Reduced
55.4% |
| Length
of Irregularities |
Reduced
52.2% |
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| These
results correspond to restructuring of the tissue. At the end
of treatment the surface of the skin was more regular in appearance
and the global profile was more uniform with stretch marks tending
to fade. These results show Siegesbeckia Orientalis Extract
to possess exciting characteristics for the treatment of stretch
marks. In addition, Siegesbeckia Orientalis Extract is shown
to possess excellent tolerance and non-toxicity. |
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